General Principles of Toxicology - Lecture 1 by Dr. S. M. Chanda - University of Zambia - Medical and Pharmaceutical Sciences-unza

Description

This foundational lecture note provides a comprehensive introduction to the principles and scope of toxicology. Authored by Dr. S. M. Chanda, the material defines toxicology as the science of poisons and explores the quantitative nature of toxicity, emphasizing the critical role of dose in determining harmful effects, from acute lethality to chronic conditions. It systematically covers key concepts including the dose-response relationship, mechanisms of toxic action across molecular, behavioral, and organ levels, and the various classes of toxic substances such as drugs, pesticides, and environmental pollutants. Designed for tertiary students in medicine, pharmacy, and toxicology programs at the University of Zambia, this resource outlines essential methodologies for measuring toxicants and toxicity, including analytical techniques and toxicity testing. The notes serve as vital revision material for understanding the evaluation of toxic agents and the application of toxicology in clinical, forensic, environmental, and regulatory contexts, supporting effective exam preparation and professional practice. Review this guide to build a solid foundation in the general principles that underpin the study of harmful chemicals and their effects on living systems.