Therapeutic Drug Monitoring (TDM) & Toxicology (Poisoning) by Mr. F. Mulenga - Clinical Biochemistry - Clinical Biochemistry-unza

Description

This comprehensive set of lecture notes on Therapeutic Drug Monitoring (TDM) and Toxicology from the Clinical Biochemistry department provides an essential resource for medical laboratory science students and clinical biochemistry professionals. Authored by Mr. F. Mulenga, the material systematically covers the principles, applications, and laboratory methods critical for the safe and effective monitoring of drug therapies and the management of poisoning. It details the vital role of TDM in optimizing drug dosage, preventing toxicity, and addressing interindividual variability in drug response, with a strong focus on pharmacogenetics. Key topics include the criteria for drug monitoring, indications for TDM, factors influencing plasma drug concentrations, and specific clinical applications for drugs such as digoxin, lithium, anticonvulsants, and immunosuppressants. The notes also explore analytical techniques, including chromatography and immunoassays, used in toxicology. This authoritative material is designed to support students in mastering the laboratory skills and clinical knowledge required for effective therapeutic drug monitoring and toxicological analysis in a tertiary healthcare setting, directly aiding in exam preparation and practical application. Review and download these notes to enhance your understanding of this critical area of clinical laboratory practice.