Topics for Pharmacology II (Systemic Therapeutics)
Find educational topics for Pharmacology II (Systemic Therapeutics) aligned with the Zambian tertiary curriculum.
Targeted Cancer Therapies
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Targeted Cancer Therapies represent a transformative area in tertiary pharmacological and oncological education, focusing on drugs that specifically interfere with molecular targets involved in cancer growth and survival. This topic is essential for Zambian university students in medicine, pharmacy, oncology, and molecular medicine programs, as it reflects the shift towards …
DMARDs and Biologics in Rheumatoid Arthritis
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This advanced pharmacology topic covers the use of disease-modifying antirheumatic drugs (DMARDs) and biologic agents in the management of rheumatoid arthritis. You will explore conventional DMARDs like methotrexate, sulfasalazine, and leflunomide, as well as biologic DMARDs targeting TNF-α, IL-6, B-cells, and T-cell co-stimulation. The content includes mechanisms of action, pharmacokinetics, …
Isoniazid Toxicity and Pyridoxine (B6) Supplementation
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Isoniazid (INH) toxicity, particularly peripheral neuropathy, is a key adverse drug reaction topic in tertiary pharmacology and infectious disease courses for Zambian students. This module explains the mechanism where INH interferes with pyridoxine (vitamin B6) metabolism, depleting this cofactor essential for neurotransmitter synthesis and leading to neuropathic symptoms. The curriculum …
Pharmacology of Antidepressants and Mood Stabilizers
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This topic covers the pharmacology of drugs used to treat mood disorders, including tricyclic antidepressants (TCAs) like amitriptyline, selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), and mood stabilizers such as lithium and valproate. For Zambian university students in medicine, psychiatry, and clinical pharmacy, this knowledge is essential for …
Pharmacology of Local Anesthetics and Toxicities
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This topic explores the pharmacology of local anesthetic agents such as lidocaine, bupivacaine, and procaine, focusing on their mechanisms of action via sodium channel blockade, pharmacokinetics, clinical uses in regional anesthesia, and management of systemic toxicity. For Zambian medical, dental, and anesthesia students, this knowledge is critical for performing safe …
Pharmacology of Anti-tuberculosis Drugs
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This topic details the pharmacology of first-line and second-line anti-tuberculosis drugs, crucial knowledge for medical, pharmacy, and clinical officer students in Zambia, a high-TB burden country. It covers the mechanism of action, pharmacokinetics, common side effects, and monitoring requirements for drugs such as Isoniazid (INH), Rifampicin, Pyrazinamide (PZA), and Ethambutol. …
Antibiotic Stewardship
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Rational antibiotic use in pulmonary infections. For Zambian medical students.
Pharmacology of Diuretics
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This topic details the pharmacology of major diuretic classes, essential knowledge for medical and pharmacy students in Zambian tertiary institutions managing hypertension, heart failure, and oedema. It covers the sites of action, mechanisms, indications, and adverse effects of loop diuretics (furosemide), thiazides (hydrochlorothiazide), potassium-sparing diuretics (spironolactone, amiloride), and osmotic diuretics …
Pharmacology of Common Emergency Drugs
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Covers key emergency drugs: epinephrine, atropine, amiodarone, naloxone, and magnesium. Focuses on indications, dosing, and side effects for ACLS, anaphylaxis, and toxicology. Essential for emergency medicine, ICU, and resuscitation training.