Autopsy and Post-Mortem Examination
Q: True or False: A biopsy is the examination of a dead body to determine the cause of death.
Did You Know?
Pulmonary carcinosarcoma shows a biphasic pattern with both malignant epithelial (carcinoma) and malignant mesenchymal (sarcoma) components. The carcinoma component is usually squamous cell carcinoma or adenocarcinoma; the sarcoma component may show spindle cells, chondroid, or osteoid differentiation. Cytologically, one may see both epithelial malignant cells and spindle malignant cells. This rare tumor is aggressive. Diagnosis can be challenging on cytology alone as both components may not be sampled. Immunohistochemistry (epithelial markers positive in carcinoma, vimentin positive in sarcoma) helps. Distinction from pleomorphic carcinoma (which has sarcomatoid but not true heterologous elements) is important.
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