Chemotherapy of Nematode Infections
Q: Mebendazole acts by inhibiting glucose uptake in parasitic worms, leading to their depletion of energy stores. True or False?
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This statement is false. An electronic (or computer) crossmatch is a method where the compatibility between a donor unit and a recipient is verified by the blood bank computer system without performing a serological crossmatch. It relies on strict criteria: 1) The patient must have two confirmed ABO and Rh typings on record. 2) The patient must have a current negative antibody screen. 3) The patient must have no history of clinically significant antibodies. If a patient has a history of a clinically significant antibody (e.g., anti-Kell, anti-Duffy), an electronic crossmatch is NOT permitted. In such cases, a full serological crossmatch, including an antiglobulin (Coombs) phase, must be performed to ensure the donor unit lacks the corresponding antigen and is compatible. The electronic crossmatch is safe and efficient but only for patients who are unlikely to have destructive antibodies.
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