DNA Replication and Fidelity
Q: What is the name of the enzyme that synthesizes a short RNA primer during DNA replication?
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Rifampin binds to the beta subunit of DNA-dependent RNA polymerase, inhibiting transcription initiation. It is bactericidal and used for tuberculosis, staphylococcal infections, and prophylaxis. Resistance arises from mutations in the rpoB gene.
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