v-GPCR (viral G-protein-coupled receptor) is a constitutively active homolog of the human IL-8 receptor. It signals independently of ligand, activating multiple pathways (like MAPK and PI3K) that promote cell proliferation and the secretion of angiogenic factors (like VEGF). This drives the characteristic blood vessel growth (angiogenesis) seen in Kaposi's sarcoma lesions.

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Zambia

• Joseph Soko – 101 pts

• Visual Pathway Lesions
• Positive and Negative Symptoms
• Hallucinations and Delusions
• Antipsychotic Medications
• Emergency: Environmental Emergencies