True. Syndrome of Inappropriate Antidiuretic Hormone (SIADH) is characterized by the persistent, non-physiological release of Antidiuretic Hormone (ADH, or vasopressin) despite normal or low plasma osmolality. This leads to excessive water reabsorption in the kidneys' collecting ducts. The retained water dilutes the sodium in the blood, causing hyponatremia (low serum sodium) and a state of volume expansion (but without edema, because the water is evenly distributed). Common causes include certain cancers (e.g., small cell lung cancer producing ectopic ADH), central nervous system disorders (stroke, infection), pulmonary diseases, and some medications. Symptoms are primarily neurological due to cerebral edema and range from headache, nausea, and confusion to seizures, coma, and death in severe cases. Treatment involves fluid restriction, addressing the underlying cause, and sometimes hypertonic saline or medications like demeclocycline.

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Zambia

• Joseph Soko – 101 pts

• Visual Pathway Lesions
• Positive and Negative Symptoms
• Hallucinations and Delusions
• Antipsychotic Medications
• Emergency: Environmental Emergencies