Immune Thrombocytopenic Purpura is an autoimmune disorder. The body's immune system mistakenly produces antibodies (usually IgG) that target specific proteins (antigens) on the surface of the patient's own platelets. These antibody-coated platelets are then recognized as 'foreign' by macrophages, primarily in the spleen. The macrophages engulf and destroy the platelets, a process called phagocytosis. This results in a low platelet count (thrombocytopenia). Importantly, the bone marrow in ITP is usually normal or even shows increased production of platelets (megakaryocytes) as it tries to compensate for the loss, but the immune destruction outpaces production.

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Zambia

• Joseph Soko – 101 pts

• Visual Pathway Lesions
• Positive and Negative Symptoms
• Hallucinations and Delusions
• Antipsychotic Medications
• Emergency: Environmental Emergencies