This statement is false. In fact, the opposite is true: squamous cell carcinoma (SCC) of the penis is significantly more common in uncircumcised men. Circumcision, especially if performed in infancy, is considered a strong protective factor against penile cancer. The underlying reason is related to chronic irritation and inflammation. In uncircumcised men, the area under the foreskin (the preputial sac) can accumulate a substance called smegma, which is a mixture of dead skin cells, oils, and moisture. This environment, combined with poor hygiene, can lead to chronic inflammation (balanitis or balanoposthitis). Furthermore, the foreskin allows for persistent infection with high-risk strains of the human papillomavirus (HPV), particularly types 16 and 18, which are strongly implicated in the development of penile SCC. Therefore, practices that reduce these risk factors—such as neonatal circumcision, good genital hygiene, and HPV vaccination—are associated with a markedly lower incidence of this malignancy.

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Zambia

• ivwananji siwale – 29 pts

• Visual Pathway Lesions
• Positive and Negative Symptoms
• Hallucinations and Delusions
• Antipsychotic Medications
• Emergency: Environmental Emergencies