Human Pedigrees and Modes of Inheritance
Q: In a standard pedigree, a shaded circle represents an affected female. True or False?
Did You Know?
The A and B alleles exhibit codominance. This means when an individual inherits both an A and a B allele (genotype A/B), both alleles are fully and equally expressed. The A allele leads to the production of A antigens, and the B allele leads to the production of B antigens on the same red blood cells, resulting in the AB phenotype. In contrast, the O allele is recessive to both A and B. An individual with one A and one O allele (A/O) will have the A phenotype because the presence of the A allele masks the expression of the non-functional O allele. The statement that A and B are dominant over O is also true, but the unique aspect of their interaction with each other is codominance.
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