Hypercalcemia of Malignancy
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Did You Know?
Infliximab is a large monoclonal antibody (a protein). Large proteins like antibodies cannot easily cross capillary walls into tissues. They are primarily confined to the plasma compartment of the blood. A volume of distribution (Vd) of about 3 liters is very low, roughly equal to the plasma volume in an adult, confirming that the drug stays mostly in the bloodstream.
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