Inborn Errors of Metabolism Screening
Q: Which of the following are typically included in newborn screening?
Did You Know?
The WNT receptor is a complex of a Frizzled family protein (a 7-transmembrane receptor) and a LRP5/6 co-receptor. When a WNT ligand binds to this complex, it initiates a conformational change that recruits the cytoplasmic adapter protein Dishevelled (DVL). This recruitment is the first step in inactivating the β-Catenin destruction complex.
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