This statement is misleading and false in its specifics. In reverse grouping, we use A1 and B reagent cells, not O cells. However, the core clue to the Bombay phenotype is indeed found in reverse grouping. A Bombay individual's red cells type as O in forward grouping (no A or B antigens). In reverse grouping, their serum will contain potent anti-A, anti-B, AND anti-H. The anti-H will agglutinate not only A1 and B reagent cells (which have H antigen) but also any other red cells except other Bombay cells. So, their serum will cause strong agglutination with both A1 and B cells (like a type O person), but if you were to also test their serum against group O reagent cells (which have H antigen), it would also agglutinate them strongly. This reaction with O cells, when a person's own cells type as O, is a red flag for Bombay phenotype. Special tests with anti-H lectin (Ulex europaeus) on the patient's red cells would confirm the absence of H antigen.

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Zambia

• Joseph Soko – 101 pts

• Visual Pathway Lesions
• Positive and Negative Symptoms
• Hallucinations and Delusions
• Antipsychotic Medications
• Emergency: Environmental Emergencies