University revision · Laboratory Management

Laboratory Notebook and Record Management

Question 1 of 1 Course: Biomedical Science(Degree)

Q1 Essay · up to 5 points

Which specific document or record should be updated to reflect the rejection and return of near-expiry controls from a supplier?

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For Trichomonas vaginalis, the most specific finding for an active, current infection is the direct visualization of motile trophozoites on a saline wet mount of vaginal secretions. This test has high specificity (close to 100%) because seeing the characteristic jerky, motile organism with flagella and an undulating membrane is definitive. However, its sensitivity is moderate (~60-70%). While highly sensitive, a positive nucleic acid amplification test (NAAT) like PCR (B) is also highly specific for the presence of T. vaginalis DNA, but theoretically, DNA could persist for some time after successful treatment, though this window is likely short. A positive culture (C) is also highly specific and indicates viable organisms. However, among the options, the wet mount is often considered the most immediately definitive visual proof in a clinical setting. A positive whiff test (D) is not specific for trichomoniasis; it is indicative of bacterial vaginosis.

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