Management of Risk and Balancing Interventions
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The volume of distribution (Vd) is a theoretical volume that relates the amount of drug in the body to its concentration in the blood. It is a characteristic property of the drug itself, describing how widely it distributes out of the blood and into tissues. Vd does not change with the dose administered. A larger dose will give a higher concentration, but the ratio (Amount in body / Concentration) remains constant.
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