The final and most critical safety check performed in the transfusion laboratory is the major crossmatch, or compatibility test. This test directly mixes the recipient's serum (which contains antibodies like anti-A and anti-B) with a sample of the donor's red blood cells that are about to be issued for transfusion. The test is designed to detect any clinically significant antibodies in the recipient's blood that could react with antigens on the donor's red cells. If the crossmatch is positive (shows agglutination or hemolysis), that specific unit of blood cannot be transfused to that patient. This step acts as a final verification that complements the ABO typing of both donor and recipient, catching errors or the presence of unexpected antibodies that could cause a transfusion reaction.

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Zambia

• Joseph Soko – 101 pts

• Visual Pathway Lesions
• Positive and Negative Symptoms
• Hallucinations and Delusions
• Antipsychotic Medications
• Emergency: Environmental Emergencies