Primary and Secondary Immunodeficiencies

question 1 of 4 course: Biomedical Science(Degree)
question 1 of 4 course: Biomedical Science(Degree)

Q: Which component of the immune system is defective in Severe Combined Immunodeficiency (SCID)?

Did You Know?

True. One of AKT's key pro-survival functions is to phosphorylate the pro-apoptotic protein BAD. Phosphorylated BAD is sequestered by 14-3-3 proteins in the cytoplasm, preventing it from migrating to the mitochondria and inhibiting anti-apoptotic Bcl-2 family members. This inhibits the intrinsic pathway of apoptosis, allowing the cell to survive.

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