Adsorption is a critical serological technique used in blood bank immunohematology to separate or remove specific antibodies from a serum sample. The process involves mixing the patient's serum (containing antibodies) with red blood cells (RBCs) that have the corresponding antigens. The antibodies bind (adsorb) to these antigens on the RBCs. The mixture is incubated, often at 37°C, and then centrifuged. The RBCs, now coated with antibody, are packed into a pellet. The supernatant serum is removed. This serum is now 'adsorbed' – it no longer contains the antibodies that reacted with the antigens on the RBCs used. There are two main types: 1) **Autologous Adsorption**: Uses the patient's own treated RBCs to remove autoantibodies, allowing detection of underlying alloantibodies. 2) **Allogeneic Adsorption**: Uses RBCs from a selected donor with a known phenotype to remove specific alloantibodies, helping to identify antibodies in complex sera. The adsorbed serum is then retested against reagent cells to identify remaining antibodies.

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Zambia

• Joseph Soko – 101 pts

• Visual Pathway Lesions
• Positive and Negative Symptoms
• Hallucinations and Delusions
• Antipsychotic Medications
• Emergency: Environmental Emergencies