False. The direct IHC method is generally less sensitive than indirect methods. In the direct method, the detectable label (enzyme or fluorochrome) is conjugated directly to the primary antibody. This means only one label molecule is delivered per primary antibody bound. In contrast, indirect methods (like two-step indirect, ABC, or polymer methods) employ a secondary antibody or a detection complex. These can bind to multiple sites on the primary antibody, delivering many label molecules to a single antigen site. This signal amplification makes indirect methods significantly more sensitive, allowing for the detection of antigens present at low concentrations. The direct method is simpler and faster but is reserved for antigens that are abundant or when simplicity is prioritized over sensitivity.

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Zambia

• ivwananji siwale – 29 pts

• Visual Pathway Lesions
• Positive and Negative Symptoms
• Hallucinations and Delusions
• Antipsychotic Medications
• Emergency: Environmental Emergencies