Sampling Methods and Sample Size Calculation
Q: A researcher wants to study the entire population of a small town. What sampling method is she using?
Did You Know?
This statement is true. The Activated Clotting Time (ACT) is a point-of-care test that is distinct from laboratory tests like PT and APTT, which are performed on platelet-poor plasma. The ACT is performed on a fresh sample of whole blood. The test involves adding a coagulation activator (such as celite, kaolin, or silica) directly to the blood sample in a specialized tube or cartridge. The instrument then measures the time it takes for a clot to form. Using whole blood means the test reflects the contribution of all cellular elements, including platelets, and is affected by hematocrit. Its simplicity and speed make it ideal for real-time monitoring of high-dose heparin therapy in settings like cardiac surgery, interventional cardiology, and hemodialysis, where rapid results are critical.
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