Microangiopathic Hemolytic Anemia (MAHA) occurs when red blood cells are physically sheared and destroyed as they try to force their way through countless microscopic clots within small blood vessels. This mechanical damage creates unique, fragmented red cell shapes. On a blood film, you see schistocytes (helmet cells, triangle cells), which are broken pieces of red cells. This finding is a key diagnostic clue for MAHA. Conditions like Thrombotic Thrombocytopenic Purpura (TTP), Hemolytic Uremic Syndrome (HUS), and Disseminated Intravascular Coagulation (DIC) are classic causes. The process also consumes platelets (leading to thrombocytopenia) and can damage organs like the kidneys and brain.

Break down complex topics into smaller, manageable chunks for easier recall.

Zambia

• Naomi Miselo – 31 pts

• Visual Pathway Lesions
• Positive and Negative Symptoms
• Hallucinations and Delusions
• Antipsychotic Medications
• Emergency: Environmental Emergencies