Tissue Processing Principles and Stages
Q: What is the purpose of the 'infiltration' step in tissue processing?
Did You Know?
True. Chronic infections (e.g., H. pylori in the stomach, HBV/HCV in the liver) cause persistent tissue inflammation. Immune cells and infected epithelial cells continuously produce cytokines (like TNF-α, IL-1) that activate the NF-κB pathway. This chronic NF-κB activation promotes a pro-survival, pro-proliferative, and pro-inflammatory microenvironment that drives carcinogenesis.
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