University revision · Blood Transfusion Science

Transfusion Transmissible Infections (HIV)

Question 1 of 63 Course: Biomedical Science(Degree)

Which patient population is most susceptible to 'transfusion-transmitted cytomegalovirus' (TT-CMV) and why?

Save your progress

Did you know?

The HIF (Hypoxia-Inducible Factor) pathway is the primary cellular response to low oxygen levels (hypoxia). In normoxia, HIF-α subunits are hydroxylated, recognized by the VHL E3 ubiquitin ligase, and degraded. In hypoxia, this degradation is blocked, allowing HIF-α to accumulate, dimerize with HIF-β, and translocate to the nucleus. There, it activates the transcription of hundreds of genes involved in adaptation to hypoxia, including VEGF (vascular endothelial growth factor), which stimulates the growth of new blood vessels (angiogenesis) to supply the tumor with oxygen and nutrients.

Memory tip

Break down complex topics into smaller, manageable chunks for easier recall.

Up next

Hepatitis B Virus Infection

Start next revision

Top performers

lP loveness Phiri 1167

Trending revisions

Focus tracker

Time on task: 0 min