Tumour Immune Evasion

question 1 of 9 course: Biomedical Science(Degree)
question 1 of 9 course: Biomedical Science(Degree)

Q: The inhibitory receptor PD-1 on T cells binds to its ligand PD-L1, which is often overexpressed on tumor cells, leading to T cell exhaustion.

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Oncogenes are derived from normal proto-oncogenes. Mutations (e.g., Ras, Myc, HER2) lead to constitutive activation, driving uncontrolled cell growth and survival.

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