Tumour Immune Evasion
Q: The inhibitory receptor PD-1 on T cells binds to its ligand PD-L1, which is often overexpressed on tumor cells, leading to T cell exhaustion.
Did You Know?
Oncogenes are derived from normal proto-oncogenes. Mutations (e.g., Ras, Myc, HER2) lead to constitutive activation, driving uncontrolled cell growth and survival.
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