Biomedical Science(Degree) · Fourth Year · BIO402
Clinical Biochemistry
Clinical Biochemistry examines the chemical processes within the human body and their relevance to disease diagnosis and monitoring. This course is central to biomedical science exam preparation, as it covers laboratory tests commonly used in clinical settings across Zambia. Students learn to interpret biochemical results …
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Clinical Biochemistry examines the chemical processes within the human body and their relevance to disease diagnosis and monitoring. This course is central to biomedical science exam preparation, as it covers laboratory tests commonly used in clinical settings across Zambia. Students learn to interpret biochemical results related to organ function, metabolism, and disease progression. The course supports career paths in diagnostic laboratories, research institutions, and healthcare facilities. By combining theoretical knowledge with practical relevance, learners gain skills that enhance analytical thinking, laboratory competence, and professional readiness in biomedical and clinical science fields.
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Topic 64
Acid-Base Disorders: Metabolic Causes
Focuses on metabolic acidosis and alkalosis: causes, anion gap, compensation, and diagnostic approach. Uses blood gas interpretation. Core knowledge for Zambian medical and critical care students managing ICU patients.
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Topic 65
Respiratory Acidosis and Alkalosis
Covers pathophysiology of respiratory acid-base disorders: hypoventilation vs. hyperventilation. Discusses acute/chronic forms, causes, and renal compensation. Essential for Zambian clinical students interpreting ABGs in respiratory diseases.
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Topic 66Coming soon
Calcium and Phosphate Homeostasis
Detailed study of PTH, vitamin D, and calcitonin in regulating blood calcium and phosphate. Covers hyper/hypocalcemia and bone metabolism. Fundamental for Zambian biomedical and endocrine students.
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Topic 67
Therapeutic Drug Monitoring Principles
Covers pharmacokinetics, indications for TDM, sampling timing, and interpretation for drugs with narrow therapeutic indices. Essential for Zambian pharmacy and lab science students to optimize drug therapy safely.
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Topic 68
Endocrine Causes of Hypercalcemia
Focuses on primary hyperparathyroidism, hypervitaminosis D, MEN syndromes, and PTHrP-mediated hypercalcemia. Covers diagnostic workup and differentials. Advanced topic for Zambian endocrinology and internal medicine students.
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Topic 69
Disorders of Amino Acid Metabolism
Covers inherited disorders like phenylketonuria (PKU), alkaptonuria, homocystinuria, and maple syrup urine disease. Examines biochemical defects, clinical features, and diagnostic metabolites. Essential for Zambian genetics and metabolic medicine students.
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Topic 70
Lipid Disorders and Fatty Acid Oxidation
Covers medium-chain acyl-CoA dehydrogenase deficiency (MCADD) and other fatty acid oxidation defects. Examines hypoketotic hypoglycemia and metabolic crises. Critical for Zambian students in metabolic medicine and pediatrics.
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Topic 71
Mitochondrial and Peroxisomal Disorders
Explores defects in mitochondrial DNA (e.g., MELAS) and peroxisomal biogenesis (e.g., Zellweger syndrome). Covers clinical features like lactic acidosis, neuropathy, and dysmorphia. Advanced topic for Zambian genetics and biochemistry students.
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Topic 72Coming soon
Lysosomal Storage Diseases
Covers mucopolysaccharidoses (e.g., Hurler syndrome), sphingolipidoses (e.g., Tay-Sachs), and other lysosomal enzyme deficiencies. Discusses accumulated substrates and clinical progression. Important for Zambian genetics and pediatric students.