Biomedical Science(Degree) · Fourth Year · BIO402
Clinical Biochemistry
Clinical Biochemistry examines the chemical processes within the human body and their relevance to disease diagnosis and monitoring. This course is central to biomedical science exam preparation, as it covers laboratory tests commonly used in clinical settings across Zambia. Students learn to interpret biochemical results …
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Clinical Biochemistry examines the chemical processes within the human body and their relevance to disease diagnosis and monitoring. This course is central to biomedical science exam preparation, as it covers laboratory tests commonly used in clinical settings across Zambia. Students learn to interpret biochemical results related to organ function, metabolism, and disease progression. The course supports career paths in diagnostic laboratories, research institutions, and healthcare facilities. By combining theoretical knowledge with practical relevance, learners gain skills that enhance analytical thinking, laboratory competence, and professional readiness in biomedical and clinical science fields.
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Topic 73
Pharmacogenetics and Drug Metabolism
Examines genetic variations affecting drug response, including G6PD deficiency, CYP450 polymorphisms, and malignant hyperthermia. Covers clinical implications for drug safety. Relevant for Zambian pharmacology and laboratory medicine students.
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Nutritional Assessment and Anthropometry
Covers BMI, waist circumference, serum proteins (albumin, prealbumin), vitamin/mineral assays, and functional tests. Teaches comprehensive nutritional evaluation. Essential for Zambian dietetics and public health students.
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Topic 75
Trace Element Deficiencies
Examines iron, zinc, copper, selenium, and iodine deficiencies. Covers biochemical roles, clinical syndromes, and laboratory diagnosis. Critical for Zambian nutrition and laboratory science students.
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Topic 76
Diabetes Mellitus: Biochemical Basis
Covers pathophysiology of type 1 and type 2 DM, insulin action, glucagon, ketogenesis, and diagnostic criteria (glucose, HbA1c). Essential for Zambian medical and biomedical students managing this prevalent disease.
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Topic 77
Adrenal Cortex Hormones and Disorders
Covers cortisol, aldosterone, and adrenal androgen synthesis. Discusses Cushing's syndrome, Addison's disease, and congenital adrenal hyperplasia. Vital for Zambian endocrinology and internal medicine students.
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Topic 78
Pituitary-Adrenal Axis Assessment
Covers dynamic testing for adrenal function including ACTH stimulation test, dexamethasone suppression test, and CRH stimulation. Critical for Zambian endocrinology students diagnosing Cushing's and Addison's disease.
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Topic 79
Gonadal Hormones and Disorders
Covers testosterone, estrogen, progesterone synthesis and regulation. Discusses hypogonadism, PCOS, and menstrual cycle disorders. Essential for Zambian reproductive endocrinology and gynecology students.
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Topic 80
Bone Metabolism Markers
Covers biochemical markers of bone formation (alkaline phosphatase, osteocalcin) and resorption (CTX, NTX). Discusses use in osteoporosis and metabolic bone disease monitoring. Important for Zambian rheumatology and endocrinology students.
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Topic 81
Tumor Markers in Clinical Practice
Covers PSA, CA-125, CEA, AFP, hCG and other tumor markers. Discusses appropriate use, limitations, and interpretation in cancer screening/diagnosis/monitoring. Essential for Zambian oncology and laboratory medicine students.