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Biomedical Science(Degree) · Third Year · BIO306

Toxicology and Pharmacology

Toxicology and Pharmacology provides a comprehensive understanding of how drugs and toxic substances interact with biological systems. This course is essential for biomedical science students preparing for examinations and careers in healthcare and laboratory sciences in Zambia. It covers drug actions, adverse effects, toxicity, and …

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Toxicology and Pharmacology provides a comprehensive understanding of how drugs and toxic substances interact with biological systems. This course is essential for biomedical science students preparing for examinations and careers in healthcare and laboratory sciences in Zambia. It covers drug actions, adverse effects, toxicity, and safety principles that are commonly tested in biomedical programs. Students gain analytical skills needed to interpret drug-related data and toxicological reports. The course supports career opportunities in pharmaceutical research, clinical laboratories, regulatory agencies, and public health institutions. By linking pharmacological theory to real-world health applications, learners build competence that is valuable for both academic success and professional practice.

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    Antiviral Drug Resistance

    This advanced topic examines the mechanisms by which viruses develop resistance to antiviral drugs, including mutation of viral enzyme targets (e.g., HIV reverse transcriptase, HBV polymerase, influenza neuraminidase), reduced drug activation, and enhanced drug efflux. It covers the clinical implications, methods for resistance testing (genotypic/phenotypic assays), and strategies to prevent and manage resistance (combination therapy, adherence). For Zambian tertiary students in pharmacology and infectious diseases, this is critical for optimizing treatment regimens, especially for HIV and hepatitis, and is a key focus area in advanced therapeutics.

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