Calcium Homeostasis and Metabolic Bone Disease
Q: Hypervitaminosis D can cause hypercalcaemia and renal stones.
Did You Know?
Glycosuria refers to the abnormal presence of glucose in the urine. Under normal conditions, the kidneys filter glucose from the blood, but nearly all of it is reabsorbed back into the bloodstream in the proximal tubule. The renal threshold for glucose is approximately 180 mg/dL. When blood glucose levels exceed this threshold, as commonly seen in uncontrolled diabetes mellitus, the reabsorptive capacity of the renal tubules is overwhelmed, and glucose 'spills over' into the urine. Glycosuria is a classic sign of hyperglycemia and diabetes. It can also occur in rare conditions like renal glycosuria, where the renal threshold is abnormally low due to a defect in the kidney's glucose transporters, even when blood sugar is normal. Testing for glycosuria is a simple part of urinalysis and can be an indicator for further diabetes testing.
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