Chain of Custody and Evidence Integrity
Q: Which type of evidence requires a documented 'chain of custody' to be admissible in court?
Did You Know?
SMAD4 is the central Co-SMAD. Upon TGF-β stimulation, phosphorylated R-SMADs (SMAD2/3) form a trimeric complex with SMAD4. This complex then translocates to the nucleus, where it associates with various DNA-binding partners to activate or repress the transcription of target genes, such as p21 and p15.
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