Clinical Enzymology

Clinical Enzymology is a fundamental topic for Zambian university students studying Biomedical Sciences or Laboratory Technology. It involves the assay and interpretation of plasma enzyme activities for diagnostic purposes. This topic covers enzymes of diagnostic value such as ALT, AST, ALP, GGT, CK, and LDH, including their isoenzymes. Students will learn about factors affecting assay results, enzyme patterns in diseases like myocardial infarction, liver disorders, and muscle diseases, and the concept of macroenzymes. Mastery of clinical enzymology is essential for passing professional diploma and degree examinations and is a core skill for any biomedical scientist working in hospital laboratories across Zambia, enabling accurate diagnosis and monitoring of patient conditions.