A well-known and common side effect of alpha-1 adrenergic blockers like tamsulosin, alfuzosin, and doxazosin is retrograde ejaculation. These medications work by relaxing smooth muscle in the prostate and bladder neck. During ejaculation, this relaxation can prevent the normal closure of the bladder neck, causing semen to flow backward into the bladder instead of out through the urethra. Patients experience a 'dry orgasm' (orgasm with little or no visible ejaculate). Other common side effects include dizziness, orthostatic hypotension (a drop in blood pressure upon standing causing lightheadedness), nasal congestion, and fatigue. It's important to counsel patients about these potential effects, especially retrograde ejaculation, as it can affect fertility.

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Zambia

• Joseph Soko – 101 pts

• Visual Pathway Lesions
• Positive and Negative Symptoms
• Hallucinations and Delusions
• Antipsychotic Medications
• Emergency: Environmental Emergencies