HBx does not have direct DNA-damaging activity. Instead, it localizes to the mitochondria and can disrupt mitochondrial function. This can lead to the production of reactive oxygen species (ROS), which are potent DNA-damaging agents. The resulting oxidative DNA damage, if not repaired properly, contributes to the mutations and genomic instability that drive hepatocellular carcinoma development.

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Zambia

• Naomi Miselo – 31 pts

• Visual Pathway Lesions
• Positive and Negative Symptoms
• Hallucinations and Delusions
• Antipsychotic Medications
• Emergency: Environmental Emergencies