Disease Concepts and Terminology
Q: What is the normal range for human body temperature (oral) in degrees Celsius?
Did You Know?
False. While NF-κB can and does induce the expression of cyclin D1 and other cell cycle regulators, this is not its primary or defining function. The core functions of NF-κB are the regulation of immune responses, inflammation, and cell survival. In cancer, its major contribution is often through creating a pro-inflammatory and pro-survival microenvironment, inhibiting apoptosis, and promoting angiogenesis. Its role in direct cell cycle promotion, while real, is generally secondary to these other functions.
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