Electrolyte Imbalances and ECG Changes
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H1 antagonists block histamine effects, leading to: 1) Reduction of allergic symptoms (itching, urticaria, rhinorrhea, sneezing). 2) Sedation (especially 1st generation). 3) Antiemetic and antivertigo effects (motion sickness). 4) Anticholinergic effects (dry mouth, blurred vision, urinary retention). 5) Local anesthetic effects (some agents). 6) Suppression of cough (some agents).
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