True. KSHV encodes v-Bcl-2 (also known as KS-Bcl-2 or ORF16), a viral homolog of the cellular anti-apoptotic protein Bcl-2. Like its cellular counterpart, v-Bcl-2 functions to inhibit apoptosis by binding and sequestering pro-apoptotic Bcl-2 family members such as Bax and Bak. This prevents them from forming pores in the mitochondrial outer membrane and releasing cytochrome c, thereby blocking the intrinsic pathway of apoptosis. This enhances the survival of KSHV-infected cells, which is advantageous for the virus and contributes to tumorigenesis.

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Zambia

• Chita katowando – 271 pts

• Visual Pathway Lesions
• Positive and Negative Symptoms
• Hallucinations and Delusions
• Antipsychotic Medications
• Emergency: Environmental Emergencies