Familial Medullary Thyroid Carcinoma (FMTC)
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Transforming Growth Factor-beta (TGF-β) is a potent immunosuppressive cytokine secreted by many tumors. It inhibits the activation and proliferation of T cells and NK cells, promotes the differentiation of regulatory T cells, and inhibits the function of antigen-presenting cells, collectively creating an environment that suppresses anti-tumor immunity.
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