Gene Therapy

Gene therapy is an advanced tertiary education topic for Zambian students pursuing degrees or diplomas in biomedical sciences, genetics, biotechnology, and medical laboratory technology. This subject covers the principles, approaches, and technical aspects of gene therapy, including somatic vs. germline therapy, in vivo vs. ex vivo methods, and viral and non-viral delivery systems such as adenoviruses, retroviruses, liposomes, and naked DNA. Learners will explore RNA-based therapies like antisense oligonucleotides, RNA interference, and ribozymes, as well as the ethical, social, and safety considerations relevant to clinical applications. The topic aligns with university and college syllabi in Zambia, preparing students for examinations, research, and emerging biotechnological careers. Emphasis is placed on the therapeutic potential for genetic disorders, cancer, and infectious diseases, equipping Zambian tertiary learners with cutting-edge knowledge for academic success and professional engagement in genomics and personalised medicine.