University revision · General Pathology

General and Systemic Pathology

Question 1 of 10 Course: Medicine(Degree)

Metaplasia is a reversible change in which one adult cell type is replaced by another. Which of the following is a primary cause?

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Allopurinol inhibits xanthine oxidase, the enzyme that converts hypoxanthine to xanthine and xanthine to uric acid. By blocking this pathway, hypoxanthine and xanthine accumulate in plasma. These compounds are more water-soluble than uric acid and are excreted in urine, reducing uric acid production.

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