Herpes simplex virus (HSV) infection in the respiratory tract can be identified in sputum cytology by the presence of enlarged, multinucleated epithelial cells with nuclear molding (where nuclei conform to each other's shapes) and homogeneous, ground-glass chromatin. Intranuclear eosinophilic inclusions (Cowdry type A) may also be seen. These cytopathic changes are characteristic of herpesvirus family infections and can occur in HSV pneumonia or tracheobronchitis, especially in immunocompromised patients. Distinguishing herpes from other viruses like cytomegalovirus (which has owl's eye inclusions) or measles (which has both intranuclear and cytoplasmic inclusions) is important for diagnosis and management, as herpes infections may require specific antiviral therapy.

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Zambia

• loveness Phiri – 1084 pts

• Visual Pathway Lesions
• Positive and Negative Symptoms
• Hallucinations and Delusions
• Antipsychotic Medications
• Emergency: Environmental Emergencies