Nuclear molding is a characteristic cytomorphological feature of small cell (oat cell) carcinoma in sputum. This occurs when the nuclei of adjacent tumor cells conform to each other's shapes due to their high density and fragile nature. The cells are typically small with scant cytoplasm, finely granular 'salt-and-pepper' chromatin, and inconspicuous nucleoli. Recognizing nuclear molding helps distinguish small cell carcinoma from other malignancies like lymphoma or carcinoid tumors, which may have similar cell size but lack this specific architectural feature.

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Zambia

• Joseph Soko – 101 pts

• Visual Pathway Lesions
• Positive and Negative Symptoms
• Hallucinations and Delusions
• Antipsychotic Medications
• Emergency: Environmental Emergencies