University revision · Hematology

Multiple Myeloma and Paraproteinaemias

Question 1 of 4 Course: Biomedical Science(Degree)

A monoclonal gammopathy is often associated with multiple myeloma. True or false?

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True. Each PCR cycle includes a high-temperature step (around 95°C) to denature (separate) the DNA double helix. A regular DNA polymerase would be destroyed at this temperature. Taq polymerase, isolated from a thermophilic bacterium, remains stable and active throughout these cycles, making automated PCR possible.

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