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Musculoskeletal System Toxicology

question 1 of 12 course: Biomedical Science(Degree)
question 1 of 12 course: Biomedical Science(Degree)

Q: What is the name of the condition caused by excessive vitamin A intake?

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PCH is a rare form of autoimmune hemolytic anemia, often seen in children after a viral infection. It is caused by the Donath-Landsteiner antibody, which is a biphasic IgG autoantibody. It binds to red cells in the cold (periphery) and fixes complement; when the blood warms up (core), complement activation causes intravascular hemolysis, leading to hemoglobinuria.

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Did You Know?

PCH is a rare form of autoimmune hemolytic anemia, often seen in children after a viral infection. It is caused by the Donath-Landsteiner antibody, which is a biphasic IgG autoantibody. It binds to red cells in the cold (periphery) and fixes complement; when the blood warms up (core), complement activation causes intravascular hemolysis, leading to hemoglobinuria.

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