Onchocerca Corneal Microfilariae
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A well-known side effect of 5-alpha reductase inhibitors (like finasteride and dutasteride) is sexual dysfunction, most commonly decreased libido (sex drive), erectile dysfunction, and ejaculation disorders (such as reduced ejaculate volume). These drugs work by blocking the conversion of testosterone to dihydrotestosterone (DHT), a more potent androgen. While this shrinks the prostate, it also reduces DHT levels throughout the body, which can impact sexual function. Other potential side effects include gynecomastia (breast enlargement). It's important for patients and clinicians to discuss these potential side effects when considering this treatment. In contrast, alpha-blockers (like tamsulosin) are more associated with side effects like dizziness, orthostatic hypotension (a drop in blood pressure upon standing), and retrograde ejaculation (where semen goes into the bladder).
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