Ovarian and Fallopian Tube Pathology
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Vancomycin resistance in enterococci (VRE) often involves alteration of the drug target: replacement of D-alanyl-D-alanine in peptidoglycan precursors with D-alanyl-D-lactate, which reduces vancomycin binding. This is encoded by van gene clusters acquired via plasmids or transposons.
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