This stage is called **Transduction**. It is the first step in the pain pathway. At the site of tissue injury or damage, chemical mediators (like prostaglandins, bradykinin) are released. These chemicals activate specialized nerve endings called nociceptors. The nociceptors then convert (transduce) this chemical and mechanical energy from the painful stimulus into an electrical nerve impulse. This impulse is the signal that will then be transmitted along nerve fibers towards the spinal cord and brain. Understanding this stage is key, as many analgesic medications (like NSAIDs) work by interfering with the chemical mediators involved in transduction.

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Zambia

• Naomi Miselo – 31 pts

• Visual Pathway Lesions
• Positive and Negative Symptoms
• Hallucinations and Delusions
• Antipsychotic Medications
• Emergency: Environmental Emergencies