Parathyroid Hormone and Calcium Homeostasis
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About this topic
This topic covers the physiology of parathyroid hormone (PTH) and its central role in calcium and phosphate homeostasis. Zambian tertiary students will learn the three primary actions of PTH: 1) activating osteoclasts to mobilize calcium from bone, 2) increasing renal tubular reabsorption of calcium and excretion of phosphate, and 3) stimulating renal conversion of vitamin D to its active form (calcitriol), which enhances intestinal calcium absorption. Understanding this integrated system is foundational for grasping the pathologies of hyperparathyroidism and hypoparathyroidism. This knowledge is crucial for university examinations in physiology and systemic pathology and is directly applicable to managing disorders of bone metabolism and renal stone disease in clinical practice in Zambia.
What you'll practise (1 question)
- What is the name of the hormone produced by the parathyroid glands that regulates calcium levels?
Answer each question above to see the correct answer and a full explanation.