Pediatrics: Neonatal Jaundice
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Second-generation H1 antagonists (e.g., azelastine, olopatadine) are more selective for peripheral H1 receptors and have poor penetration into the central nervous system (CNS). When used topically in the eye, they provide effective local relief of itching and redness without causing systemic side effects like sedation, dry mouth, or blurred vision that are common with first-generation agents.
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