Pharmacokinetics & Pharmacodynamics
Q: A 57-year-old man was in the hospital after a surgical procedure complained of severe abdominal pain. The physician decided to start analgesic treatment with an opioid. The drugs he was considering were morphine (10 mg IM) and buprenorphine (0.3 mg IM). Morphine is a full agonist at mu (µ) opioid receptors, whereas buprenorphine is a partial agonist at the same receptors. The above-mentioned doses of the two drugs are equi-effective. Which of the following pairs of statements correctly defines the potency and efficacy of morphine and buprenorphine?
Did You Know?
The lacrimatory nucleus (which provides parasympathetic secretomotor fibers for lacrimation) is associated with the facial nerve (CN VII) via the greater petrosal nerve and pterygopalatine ganglion. It is not associated with the oculomotor nerve (CN III).
Social Sharing!
Share your knowledge:
Zambia