True. This statement is accurate and reflects a key method in forensic anthropology for estimating age in individuals who have not yet reached skeletal maturity (subadults). Long bones, such as the femur, tibia, and humerus, grow from distinct centers: the shaft (diaphysis) and the ends (epiphyses). During growth, these portions are separated by a layer of cartilage known as the epiphyseal plate (or growth plate). As an individual ages, this cartilage gradually ossifies (turns to bone) in a predictable sequence and timeframe. The point where the diaphysis and epiphysis fuse becomes visible as an epiphyseal line. By examining which epiphyses are unfused, partially fused, or completely fused, and comparing these findings to established osteological standards for different ages and sexes, a forensic anthropologist can provide a reliable age-at-death estimate. This method is most accurate for individuals under approximately 25 years old, after which most skeletal growth is complete and other age indicators (like changes to the pubic symphysis or rib ends) must be used.

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